Research article

SCHIFF’S BASES PHENAZINAMINES AND ITS ANTIMICROBIAL ACTIVITY

Gaikwad Sanyogita U., Dr. Sonawane Gajanan M., Dr. Kale Mayura A.

Online First: December 22, 2022


Pharmaceutical chemistry is a science that makes use of the general laws of chemistry to study drugs, viz., their preparation, chemical nature, composition, structure, influence on an organism and studies of the physical and chemical properties of drugs, the methods of quality control, and the conditions of their storage. Heterocycles are an important class of compounds, making up more than half of all known organic compounds. Heterocycles are present in a wide variety of drugs, most vitamins, many natural products, biomolecules, and biologically active compounds, including antitumor, antibiotic, anti-inflammatory, antidepressant, antimalarial, anti-HIV, antimicrobial, antibacterial, antifungal, antiviral, antidiabetic, herbicidal, fungicidal, and insecticidal agents. Also, they have been frequently found as a key structural unit in synthetic pharmaceuticals and agrochemicals.

Keywords

Phenazinamines, Antimicrobial, Schiff’s bases, Docking, Heterocyclic