PHARMACOLOGICAL AND PHARMACOGNOSTICAL EXTRACTION AND EVALUATION FOR ANTI ULCER, ANTI OXIDANT ACTIVITY OF BEETAVULGARIS EXTRACTS IN EXPERIMENTS

Peptic ulcer disease is a serious gastrointestinal disorder that requires well targeted therapeutic strategy. A number of drugs including proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer, but clinical evaluation of these drugs has shown incidence of relapse, side effects and drug interactions. This has been rational for the development of new anti ulcer drugs and search for novel molecules has been extended to herbal that offer better protection and relapse. The present study is to evaluate the anti ulcer activity by using herbal remedy beta vulgaris. The ethanolic extract of beta vulgaris treated groups shows a significant effect when compared to control group animals which indicating that the plant having the anti ulcer activity. And also the results showed that the ethanolic extract of the beta vulgaris having the antioxidant activity. The acute toxicity study conducted for ethanolic extract of beta vulgaris indicates that safe up to 2000mg/kg body weight. Ulcer can minimize by some life style changes like, avoid eating at least two hours before bed time and whatever foods might cause discomfort, such as alcohol, caffeine beverages (coffee and pop), fatty foods, and highly seasoned foods. It is important to try to stop smoking, since smoking has been linked to ulcer formation, reduced healing, and ulcer recurrences. Also try to minimize stress in life. Stress may worsen ulcer symptoms.