Research article

IS HEPCIDIN INDUCED ANEMIA IN OBESE INDIVIDUAL

Khalid Hassan Abdalruda

Online First: October 29, 2022


Iron deficiency anemia is common within obese human, increment level of hepcidin was notice in obese which considers as systemic regular for homeostasis the iron ,it limits iron absorption rate from intestine. Objectives: The purpose is to explore hepcidin role in induced iron deficiency anemia in obese individuals. Method: A 240 participants were entered in this work,121 were normal weight and 119 were obese .The iron- status parameters, serum hepcidin and inflammatory marker were calculated. Results: IL-6, C-RP, TIBC in addition to hepcidin were significantly higher and the data demonstrate significantly lower serum iron in the obese group and male than those non obese and female correspondingly. While Hb and ferritin establish non-significant variation among these group . Conclusions: The study resolved, High hepcidin level in obese subject involve in exacerbation iron deficiency anemia.

Keywords

Anemia , Obesity, Hepcidin