Research article

UTILITY OF TAU PROTEIN AND SOME ROUTINE LABORATORY BIOMARKERS TO DETECT COVID-19

Muayad AL-dulaimi * and Nagham Qasim Kadhim

Online First: May 25, 2023


Background: The COVID-19 is a virus that results in numerous organ failure in people as well as physiological alterations in the ratios and makeup of blood and biochemical cells, including elevated AST, ALT, and LDH levels as well as Tau Protein. However, because of their association with COVID-19, they were considered to be important disease markers. Methods: For this research, 90 participants were chosen from 30 control groups and 60 COVID-19 patients. The research materials came from the hospitals' labs in Baqubah. Results: Through examining the data from the studie, we came to the conclusion that inflammatory markers, particularly Tau protein, AST, ALT, and LDH, were favorably correlated with the severity of COVID-19. Tau protein levels increased significantly between the patient group and the control groups (P0.001). According to the Iraqi Ministry of Health's protocol for the severity of COVID-19 stages, the ranking of severity for patients in this research was based on those stages. Conclusions: There is presently indication that tau protein has practical significance. Additionally, we found a correlation between the intensity of COVID-19 and the levels of tau protein, AST, ALT, and LDH that was consistent with COVID-19 infection.

Keywords

Tau Protein, AST, ALT and LDH in COVID-19.