Research article

PHYTOCHEMICAL AND PROTECTIVE STUDY FOR PETROSELINUM SATIVUM L. (PARSLEY ) ON THE OXIDATIVE STRESS AND ANTIOXIDANT IN MALE RATS

Nadia N.H.ALMasaoodi 1 , Batool Shakir Abed Almjalawi 2,3, Nibras Al-Ibrahemi 4

Online First: September 30, 2022


This study looked at the phytochemicals in Petroselinum sativum L. (Parsley) and the antioxidant effect of the volatile oil leaves extract on the levels of the oxidative stress markers malonaldehyde (MDA), lipid peroxide (LPO), and the antioxidant GSH glutathione (GSH) enzyme in adult male rats exposed to the environment. , The rats were divided up into 5 Groups (G) G1: The control group received only normal saline (0.9%), G2: A 50 mg/kg body weight (B.W.) injection of P. sativum L. volatile oil extracts, and G3: A 100 mg/kg B.W. injection Volatile extracts of P. sativum L, G4-injection 200 mg/kg B.W250 mg/kg B.W. of P. sativum L. volatile oils of extracts administered through injection in G5 After being injected for 20, 30, and 60 days, blood began to bleed. The results show that GSH levels significantly increased at dosages of 50, 100, 200, and 250 mg/kg B.W. while MDA and LPO levels significantly decreased at those same concentrations. The aim of this study antioxidant effect for volatile oils leaves extract of parsley against environment induced free radicals oxidative stress in male rats animals.

Keywords

Petroselinum sativum L. , phytochemical , oxidative stress and antioxidant