Research article

EVALUATION OF ANTIMICROBIAL AND CYTOTOXIC ACTIVITY OF CARICA PAPAYA LEAVES AND GREEN TEA BASED HERBAL FORMULATION

Aparna.J1, Dr. Anju Cecil 2*, Dr. S Rajeshkumar3

Online First: December 16, 2022


Evaluating the antibacterial and cytotoxic properties of papaya leaves and green tea herbal extract is the major objective of this study. Green tea leaf and papaya leaf extract was prepared, and the pelletized extract was collected. Testing on pathogenic microbes such Streptococcus mutans, lactobacillus, Staphylococcus aureus, Candida albicans, Enterococcus faecalis, and Staphylococcus aureus revealed that the plant has antibacterial action. After obtaining brine shrimp eggs and placing them in the chamber, cytotoxic activity of the brine shrimp was measured after it had been there for 24 hours. According to the findings, the antibacterial activity (zone of inhibition) of green tea and papaya leaf-based herbal extracts against Enterococcus faecalis and Streptococcus mutans found to be maximum. It was found that neither the papaya leaves nor the herbal extract prepared from green tea had any cytotoxic properties. The findings of this study will support the safety assessment and synthesis of this combination of herbal extract as well as our understanding of the antibacterial and toxicological effects of this green synthesis. Thus, it is evident from this study that the synthetic herbal extract has proven to be a viable substance for future investigations in medicinal applications.

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