Research article

QUALITATIVE AND QUANTITATIVE PHYTOCHEMICAL SCREENING AND CYTOTOXICITY EVALUATION OF GERANIUM WALLICHANUM.

Fahad Said Khan1, Muhammad Akram1, Abid Rashid1, Abdul Khaliq2, Abdul hamid2

Online First: November 28, 2022


In the present period, phytomedicine is becoming more accepted as a complementary medical strategy. In the current study, phytochemical components of Geranium wallichanum were tested for cytotoxicity measures. Using accepted procedures, the phytochemicals and cytotoxicity of hydroethanolic (30:70 v/v) extract of Geranium wallichanum were determined. There have been reports of alkaloids, terpenoids, flavonoids, and phenolic acids among the constituents. Numerous chemical components in the extract that are physiologically active were discovered using high-performance liquid chromatography and Fourier-transform infrared spectroscopy. When tested against Salmonella typhi TA98 and TA100, cytotoxic tests showed non-muagenic and strong thrombolytic and week hemolytic activities. According to the study's findings, Geranium wallichanum has a large num of phytochemicals and cytotoxicity screening showed that the herb is safe for use as therapeutic purpose.

Keywords

Phytomedicine, Geranium wallichanum, cytotoxicity, herbs.