HISTOPATHOLOGICAL STUDY OF PLATELET RICH PLASMA FOR PROMOTES CORNEAL RE-EPITHELIALIZATION FOLLOWING ABRASION IN THE RABBITS

The study aimed to evaluate the beneficial effect of platelets rich plasma (PRP) on corneal re-epithelialization in rabbit. Sixteen healthy male adult rabbit were used they were randomly divided into two equal groups (control group 8, treated group 8). A 3 mm diameter trephine was used to demarcate the central epithelial region of the right eye and the epithelium within the demarcated region was mechanically removed using an Alger brush II, treated group receive immediately post operation PRP (1ml) was subconjunctival injected on injured eye, while control group left without treatment. corneal healing process follow up 14 days post treatment by histopathological examination and clinically, the result display in treated group on the14 days post operation appear good epithelial layer, less infiltration of immune cells compare to the control group there is severe odema, ulceration , vascularization, hemorrhage and high infiltration of immune cells.