IMPACT OF SMOKING ON HUMAN LIPOPROTEIN

Introduction: The most frequent form of fat in the body is triglycerides. They store any extra energy you eat and high-density lipoprotein Cholesterols (HDL-C) is known as the "good" cholesterol so it can prevent you from cardiovascular problems if you have a healthy amount. Cigarette smoking damages all organ in the body causes a variety of ailments and lowers smokers' overall health, as well as Cigarette smoking, can alter triglyceride and high-density lipoprotein Cholesterols in the blood, causing smokers to have increased triglyceride levels and decreased high-density lipoprotein Cholesterols versus people who smoke. Aim: The purpose of the study is to determine how cigarette smoking affects triglyceride and HDL-C levels when compared to non-smokers. Materials and Methods: An outpatient clinic in Baghdad, Iraq, was the subject of a cross-control study. This outpatient clinic serves as the city's primary general center, with a sizable population. The research took place from March 2021 to September 2021. Adult smokers and non-smokers of both males and females were enrolled in this study, and serum samples were pooled from blood collections from each subject. Following that, each serum product was analyzed for triglycerides and HDL-C concentration. Results: The results demonstrated that there was a significant difference in triglyceride levels and HDL-C between non-smokers and smokers. Daily cigarette smoking increased triglyceride levels in exclusive cigarette users (303.533±18.059; p < 0.05) compared to non-smokers (138.080±7.401; p < 0.05) and HDL-C was lower smokers (33.400±2.011; p < 0.05) compared to non-smokers' values (66.206±1.876; p < 0.05). Conclusion: Current smokers' triglyceride levels are stimulating for cigarettes as compared to non-smokers, which is consistent with studies in other populations. Furthermore, current cigarette smokers have lower levels of good total cholesterol than non-smokers, which has been associated with harmful cardiovascular outcomes. The direct cause of the observed differences in our study is still unknown, but future research will perhaps shed some light on it.